Description
- Treatment Power: 0.1 to 250 W Avg. Incident Power, 2.5 to 500 W PIP
- Sample Processing Capacity: 1 to 8 tubes processing
The LE220-plus Focused-ultrasonicator is a scalable, automated high-performance sample preparation instrument. With automated water works to optimize user-to-user reproducibility and remote set-up and scheduling to maximize laboratory efficiency, the LE220-plus is designed for integration with high-throughput laboratory automation. Includes integrated AFA ultraCUBE water chiller and the water conditioning module.
Specifications :
| Technical Specification | Description |
|---|---|
| Primary Applications | Cell lysis: mammalian, bacterial, yeast, cfDNA Extraction from Plasma, DNA Extraction from Dried Blood Spots, DNA/RNA/Chromatin Shearing, DNA/RNA/Total NA/Protein Extraction from FFPE, Tissue lysis and extraction |
| Treatment Power | 0.1 to 250 W Avg. Incident Power, 2.5 to 500 W PIP |
| Part Number | COV-500569 |
| Power Requirements | 100-240 VAC 500 VA, 50-60Hz |
| Operating Environment | Ambient temperature: 19 °C to 25 °C (66 °F to 77 °F) Relative humidity: 30% to 70% |
| Operating Temperature | 5 °C to 40 °C |
| Safety | Complies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements |
| Regulatory Labeling | CE, ETL Mark (for Product Safety), WEEE |
| SonoLab Version | SonoLab 8 |
| Operating System | Windows 10 |
| WCS | Yes, WCS 2.0 (Included with system) |
| Chiller | ThermoCube (included with system) |
| Sample Processing Capacity | 1 to 8 tubes parallel processing |
| Recommended Batch Size | 1 to 96 samples |
| Covaris Consumables | Individual microTUBEs, 8 microTUBE strips (rack required), 96 microTUBE plate, 8 AFA-TUBE TPX Strip, 96 AFA-TUBE TPX plate (with RFID), miniTUBEs, milliTUBEs |
| Upgrade Potential | Yes |
| Associated Accessories | L-Series Accessories |
Key Features:
- Fully automated workflow
- Powered by AFA-energetics ®
- Multiple isothermal energy delivery modes
Benefits
- Accurate, reproducible, and robust sample preparation
- Tunable, non-contact processing
- Simplify highly complex workflows
Quick Guides::
Quick Guide: DNA Shearing with LE220-plus/LE220R-plus/LE220Rsc
RNA Shearing with S, E, and LE-Series Focused-ultrasonicators
TruSight Tumor 170 DNA Shearing Quick Guide
Manuals:
E220 & LE220 (-plus, R-plus, Rsc) Setup & Instruction Manual
LE220 (-plus, R-plus, and Rsc) Setup & Instruction Manual
Posters:
High Performance Multiplexed Target Enrichment Sequencing from FFPE Tissues
Brochures:
Covaris Automation Platform Solutions for Pre-analytical Sample Preparation
LE220-plus Focused-ultrasonicator
Application Notes:
AFA-energetics®- Mediated RNA Extraction from Yeast
Mediated RNA Extraction from Yeast...... Learn More
AFA-energetics®-Mediated DNA Extraction from Yeast and Bacteria Using Scanning in a Labcyte 384-well Plate
This document describes the optimized AFA-energetics dose to lyse and extract DNA from S. cerevisiae, E. coli, & L. monocytogenes using a proprietary scanning method... Learn More
Covaris Shearing Guide for 500 Base Pairs using the 96 AFA-TUBE TPX Plate
This application note provides additional support for the current AFA-TUBE TPX shearing protocol to achieve 500 base pair (bp) DNA fragments using AFA® on the... Learn More
High-Throughput, Low Volume gDNA Extraction from Whole Blood Enabled by Covaris Adaptive Focused Acoustics® (AFA®) and AFA-TUBE® TPX
Extraction of gDNA from whole blood is the first step in multiple translational research and molecular diagnostics applications, such as next-generation sequencing, multiplex PCR, qPCR,... Learn More
Lysis and Extraction of Biomolecules from Eukaryotic and Prokaryotic Cells Powered by AFA-energetics®
Covaris developed a novel automatable approach for the extraction of biomolecules from microbial samples for analysis with mass spectrometry technologies using Adaptive Focused Acoustics® technology....... Learn More
Lysis and High Molecular Weight DNA Extraction from Eukaryotic and Prokaryotic Cells Powered by AFA-energetics®
This application note describes an automatable approach to cell lysis and extraction of high molecular weight DNA from microbial samples, which can be sequenced with... Learn More
Magnetic Bead-based Clean-up Using AFA-energetics®
When precisely tuned, this stream of Covaris Adaptive Focused Acoustic energy enables DNA shearing precisely and reliably to desired fragment sizes, in addition to gentle... Learn More
truXTRAC® FFPE RNA Extraction and Purification - Quality Metrics for Clinical Applications Powered by Adaptive Focused Acoustics® (AFA®)
FFPE RNA Extraction...... Learn More