Molecular Loop - Custom Panels
Custom NGS Panels Powered by LoopCap™ Targeted Sequencing
Hybrid capture quality with amplicon simplicity. Designed for your research.
Why Traditional Targeted Sequencing Falls Short
Hybrid capture offers great coverage but at high cost and complexity. Amplicon methods are simpler but often sacrifice uniformity and sensitivity.
LoopCap™ Delivers the Best of Both Worlds
Molecular Loop’s proprietary LoopCap™ technology uses Modified Inverse Probes (MIPs) to capture targets with hybrid-like performance, through a simplified, scalable protocol perfect for clinical and research applications.
Key Benefits of LoopCap™ Targeted Sequencing:
- Hybrid capture-like uniformity without complex workflows
- Faster turnaround times
- Automation-ready protocols
- Superior coverage and minimal allelic dropout
- Cost-effective for both small and large panels
How It Works
LoopCap™ panels utilize a simple 4-step process using Modified Inverse Probes to selectively capture target regions:
- Probe Hybridization
- Gap Filling & Ligation
- Capture Amplification
- Library Prep for Sequencing
Fully Customized to Your Research
Whether you need a focused cancer panel or a broad exome coverage design, we work with you to create a fully customized LoopCap™ panel that meets your exact study requirements.
- Panel Size: 10 targets to 1000+ targets
- Low input compatibility
- Automation-ready protocols
- Custom oligo design assistance
