Seraseq™ Tumor Mutation DNA Mix v2 AF7 HC

SeraCareSKU: SER-0710-0095

Price:
$4,447

Description

The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 7%, and is offered in a high concentration (HC) format at 25 ng/µL. Designed to assess the overall performance of your somatic mutation assay by next-generation sequencing (NGS), this unique product includes a wide range of single nucleotide variants (SNVs), insertion-deletion mutations (indels), and structural variants (SVs).

 

  • Single-vial format for daily run use
  • 40 unique multiplexed variants across 28 genes (see table in Specifications tab)
    • 20 SNVs
    • 5 SNVs that are part of homopolymers
    • 13 indels
    • 2 SVs
  • Mutation targets quantitated with digital PCR
  • Well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured within cGMP-compliant, ISO 13485-certified facilities

 

The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is formulated for use with targeted next-generation sequencing (NGS) assays that detect mutations in key oncogenes and tumor suppressor genes. The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is intended as a quality reference material for translational and disease research testing to monitor library preparation, sequencing, and variant allele detection under a given set of bioinformatics pipeline parameters. Previous Part Number: 0710-0073.

For research use only. Not for use in diagnostic procedures.

 

Specifications:

Gene List
AKTI FGFR3 JAK2 PDGFRA
APC FLT3 KIT PIK3CA
ATM FOXL2 KRAS PTEN
BRAF GNA11 MPL RET
CTNNB1 GNAQ NCOA4-RET SMAD4
EGFR GNAS NPM1 TP53
ERBB2 IDH1 NRAS/CSDE1 TPR-ALK

 

Product Sheet

COA:
10523341
10536952
10219422
10403956

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