Seraseq™ Lung & Brain CNV Mix, +12 copies

SeraCareSKU: SER-0710-0416

Title: '+12 copies
Price:
$1,116

Description

Copy number variations (CNV) are genomic changes that lead to higher (amplification) or lower (loss) gene copies in comparison to a reference genome. Cells that are affected by aberrant copy number changes for certain cancer-associated genes may experience disruption of normal cellular function and, ultimately, tumorigenesis. Next-generation sequencing (NGS) can be used to determine CNVs across multiple genes in a sequencing run. However, without a widely adopted standard for CNV profiling, NGS assays may evaluate dosage for different targets using different wet and dry methods. In response, SeraCare has developed the first disease-specific CNV reference materials to support clinical labs performing NGS-based tumor profiling of lung and brain cancer patient samples.

 

  • Single sample with three clinically-relevant CNVs (save acquisition and sequencing costs)
  • Develop, optimize, and validate your assay’s ability to detect a range of copy numbers (amplifications)
  • CNV targets precisely quantitated with digital PCR
  • Single well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured in GMP-compliant, ISO 13485-certified facilities

This specific CNV Mix for lung and brain cancer includes 12 copies.

 

Size : 1 x 20 µL

Unit : EA

 

Product Specifications
# of CNVs 3 (full gene region for EGFR, MYCN and MET)
Copy Numbers +12 copies (or 14 total copies) of each gene
Concentration 10 ng/µL
Amount 200 ng (single vial)
Buffer 1 mM Tris / 0.1 mM EDTA pH 8.0

 

Also Available:
Seraseq™ Lung & Brain CNV Mix, + 3 copies
Seraseq™ Lung & Brain CNV Mix, + 6 copies

 

Product Reports:

#10440615
#10569619

Package Insert

Product Sheet

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