Molecular assays that profile tumor mutations in solid tissue biopsies require an efficient and precise evaluation of the pre-analytic portion of their workflow prior to downstream analysis by NGS or other methods. Contrived reference material or cell line-based standard can provide a critical input in the optimization of nucleic acid extraction from very challenging FFPE tissue materials without wasting precious mutation-positive tissue samples.
We have designed this FFPE cell line-based reference sample as a negative control to support the determination of assay specificity at wildtype base positions, as well as specificity at positions affected by mutations included in all of the Seraseq RNA and DNA (Mutation Mix and Reference Material) products.
- Cell line-based negative control (WT)
- Offered as FFPE for full process assay (NGS or PCR) workflow optimization
- Well-characterized GM24385 wild-type material
- Manufactured in GMP-compliant and ISO 13485-certified facilities
|# of Variants||0|
|DNA Yield*||> 100 ng|
|RNA Yield**||> 300 ng|
*From 1x10 µm FFPE curl using Agencourt Formapure/Qubit dsDNA HS quant.
**From 1x10 µm FFPE curl using Agencourt Formapure/Qubit RNA HS quant.