LE220Rsc Focused-ultrasonicator

CovarisSKU: COV-500652



As the highest power and fastest sample processing system in the Covaris portfolio, the LE220Rsc rapidly delivers AFA-energetics® to standard SBS format plates using the scanning mode. It offers tunable acoustic energy, integration with robotic platforms, and more power than the LE220-plus and R230 Focused-ultrasonicators. This instrument enables a variety of novel high power, fast process applications such as lysis of difficult to lyse microorganisms (for example, yeast) in the 96 AFA-TUBE TPX plate and dissolution of difficult to solubilize compounds.


Specifications :

Technical Specification Description
Primary Applications Cell lysis: mammalian, bacterial, yeast, DNA/RNA/Chromatin Shearing, DNA, RNA, Protein, and Biomarker extraction, DNA/ RNA Shearing for NGS, Cell Lysis, High Molecular Weight DNA Extraction
Treatment Power 0.1 to 250 W Avg. Incident Power, 2.5 to 500 W PIP,
Part Number COV-500652
Dimensions 61 cm (width), 90 cm (depth), and 48 cm (height)
Power Requirements 100 to 240 VAC 500VA, 50 to 60 Hz
Operating Environment Ambient temperature: 19 to 25 °C (66 to 77 °F) Relative humidity: 30 to 70%
Operating Temperature 5 to 40 °C
Safety Complies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements
Regulatory Labeling CE, ETL Mark (for Product Safety), WEEE
SonoLab Version SonoLab 8
Operating System Windows 10
Chiller UltraCUBE
NGS Sample Volumes 5 to 320 µl
Recommended Batch Size 8 to 96 samples
Covaris Consumables miniTUBES, milliTUBES, microTUBES, 96 AFA-TUBE TPX plate(with RFID), 384 AFA-TUBE TPX plate (with RFID)-In development
Upgrade Potential No


Quick Guide:

Quick Guide: DNA Shearing with LE220-plus/LE220R-plus/LE220Rsc


Setup & Instruction Manual:

E220 & LE220 (-plus, R-plus, Rsc)


Application Notes:

Impact of AFA-energetics on Enzymatic Hydrolysis of Proteins

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