Description
As diagnostic testing for chromosomal translocations and other complex structural variants continues to shift from single-site methods such as Fluorescent In Situ Hybridization (FISH) and targeted reverse transcription PCR (RT-PCR) to highly multiplexed next-generation sequencing (NGS) assays, there is an increasing need for highly multiplexed reference materials covering such mutations which may be rare or difficult to obtain. SeraCare continues to innovate to address this critical market need with an updated version designed for use with NGS assays that detect gene fusions via sequencing of RNA transcripts.
- Single sample with 18 clinically-relevant RNA gene fusions
- Purified RNA format is easy to use and eliminates extraction variability
- Quantification of transcript levels by dPCR establishes ground-truth and simplifies dilutions for limit of detection (LOD) experiments
- Total RNA from well-characterized GM24385 cell line as background wild-type material
- Manufactured in GMP-compliant and ISO 13485-certified facilities
For research use only. Not for use in diagnostic procedures.
Specifications:
| Product Specifications | |
| # of Fusions | 18 |
| Concentration | 25 ng/µL |
| Amount | 625 ng |
| Format | Purified RNA |
| Buffer | 1 mM Tris, pH 8.0 |