Description
Gene amplifications and deletions, collectively called copy number variations (CNVs), are common in cancer cells and contribute to uncontrolled cell growth, drug sensitivity and resistance. To support clinical labs performing NGS-based tumor profiling of cancer patient samples and help assay developers develop and characterize the performance of their assays, SeraCare has developed a comprehensive solid tumor CNV reference material in mutation mix format.
FEATURES AND BENEFITS
- 12 clinically relevant CNVs associated with solid tumors
- Copy numbers quantified using sensitive dPCR assays and blended with the well-characterized GM24385 genomic background
- Validated by a targeted NGS panel
- Manufactured in GMP-compliant, ISO 13485-certified facilities
- The specific CNV mix includes +3 copies/ +6 copies/ +12 copies
Technical product reports