Description
- Treatment Power: 100 W Avg. Incident Power
- Sample Processing Capacity: Single tube processing
- NGS Sample Volumes: 15 to 130 µl
The E220 Focused-ultrasonicator enables multi-sample batch preparation, capable of processing a wide range of sample types and volumes. The E220 may be programed to process from 1 to 96 samples in a single batch.
Specifications:
| Technical Specification | Description |
|---|---|
| Primary Applications | Cell lysis: mammalian, bacterial, yeast, cfDNA Extraction from Plasma, DNA Extraction from Dried Blood Spots, DNA/RNA/Chromatin Shearing, DNA/RNA/Total NA/Protein Extraction from FFPE, Tissue lysis and extraction |
| Treatment Power | 100 W Avg. Incident Power |
| Part Number | COV-500239 |
| Power Requirements | 100-120, 200-240 V~ 50-60Hz, 500 VAC |
| Operating Environment | Ambient temperature: 19 °C to 25 °C (66 °F to 77 °F) Relative humidity: 30% to 70% |
| Operating Temperature | 0.5 °C to 55.0 °C |
| Safety | Complies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements |
| Regulatory Labeling | CE and ETL Mark |
| SonoLab Version | SonoLab 7 |
| Operating System | Windows 10 |
| WCS | Yes |
| Chiller | Chiller/heater re-circulating system-Not included,sold separately |
| Sample Processing Capacity | Single tube processing |
| NGS Sample Volumes | 15 to 130 µl |
| Recommended Batch Size | 1 to 96 samples |
| Covaris Consumables | microTUBE 8-strip (rack required), microTUBE 96 plate |
| Upgrade Potential | No |
| Associated Accessories | E220 Accessories |
Key Features
- Isothermal processing
- Non-contact, closed vessel
- Precisely controlled and adjustable energy delivery
- Automation ready
- Multi-sample capability
- Broad sample volume range
Benefits
- No heat damage, higher recovery
- No cross contamination, no aerosols, no clean up
- Standardized processes, highly reproducible
- Integrates into customers’ sample processing workflow
- Higher productivity, less operator intervention
- One instrument for multiple applications
Quick Guides:
DNA miniTUBE – Blue for 220 Series
DNA miniTUBE – Clear for 220 Series
DNA miniTUBE – Red for 220 Series
DNA Shearing Quick Guide: microTUBE-15 with S220/E220 Focused-ultrasonicator.
DNA Shearing with microTUBEs (<1.5kb fragments) S220/E220
Quick Guide: DNA Shearing with E220 Focused-ultrasonicator .
RNA Shearing with M220 and ME220 Focused-ultrasonicators
TruSight Tumor 170 DNA Shearing Quick Guide
Manuals:
E/LE220 Series SonoLab 7 User Manual
Brochures:
E220 / E220x (E-Series) High Performance Multi-Sample Preparation System
Formulation and Drug Delivery Breakthrough processing for poorly soluble API’s
Posters:
Optimizing a Dual Fixation Protocol to Study Protein Complexes Binding to Chromatin in vivo
Application Notes:
Automated NGS Library Preparation with Beckman Biomek FXP and Covaris E220
Key parameters for high quality library preparation are homogeneity of the library insert size and un-biased fragmentation profile, which is why Covaris AFA technology was.... Learn More
Optimizing a Dual Fixation Protocol to Study Protein Complexes Binding to Chromatin in vivo
This application note provides shearing profiles, evaluates epitope integrity each shearing time and ChIP-qPCR results obtained using single step formaldehyde fixation and dual crosslinking protocol.... Learn More
Streamlined Ultra Low Sample Input and Processing Volume Chromatin Shearing Protocols for Fly Embryos and Mammalian Cell Lines
These protocols have been optimized for both mammalian cell lines and fly embryos and reliably fragment chromatin in low volumes from down to 10,000 mammalian.... Learn More
Transitioning from custom amplicon-based parallel sequencing to hybrid capture-based sequencing in molecular pathology routine diagnostics
Molecular Pahology.... Learn More