{"product_id":"marathonrt","title":"MarathonRT","description":"\u003cp\u003e\u003cstrong\u003eMarathonRT\u003cb\u003e\u003csup\u003e\u003cspan\u003e®\u003c\/span\u003e\u003c\/sup\u003e\u003c\/b\u003e\u003csup\u003e \u003c\/sup\u003e\u003c\/strong\u003epurified from \u003cem\u003eEubacterium rectale\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eis a first-generation, processive reverse transcriptase used to create cDNA from any RNA template.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHighlights:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003eOptimized Specific Activity:\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003eEach unit (U) of MarathonRT is defined as the amount of enzyme that incorporates 1 nmol of dTTP in 30 minutes at 42 °C with poly(rA)•oligo(dT)18 substrate\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003eKit-Specific Enzyme Content:\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003eThe 20-reaction kit contains\u003cspan\u003e \u003c\/span\u003e\u003cb\u003e400 U total enzyme\u003c\/b\u003e, provided at 20 U\/µL in a convenient 20 µL aliquot—sufficient for robust first-strand synthesis in 20 standard reactions (1× RT mix)\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003eHighly-Processive cDNA Synthesis:\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003eMarathonRT consistently produces ≥90% full-length cDNA products up to 8 kb, with only a modest drop on 9.6 kb templates\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003eFast and Synchronous Reverse Transcription:\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003eCopies long, structured RNAs at a constant speed of ~25 nt\/s without pausing at stable RNA motifs\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003eSensitive Detection of RNA Modifications:\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003eCompatible with DMS-MaPseq and SHAPE-MaP, enabling direct probing of RNA secondary structure across full-length transcripts.\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003eStructure-Guided Design:\u003c\/b\u003e\u003cspan\u003e \u003c\/span\u003eCrystal structures of the\u003cspan\u003e \u003c\/span\u003e\u003ci\u003eE. rectale\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003ematurase RT domain reveal a unique α-loop and RT0 motif that mediate high processivity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003e\u003cspan\u003eNow Available – UltraMarathonRT\u003cstrong\u003e\u003csup\u003e®\u003c\/sup\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e, \u003c\/span\u003ea next-generation, ultra-processive reverse\u003c\/p\u003e","brand":"RNA Connect","offers":[{"title":"Default Title","offer_id":45503371804716,"sku":"RNC-100035","price":844.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0377\/2163\/6908\/files\/MarathonRT_Microtube_3000.jpg?v=1778085883","url":"https:\/\/dmarkbio.com\/products\/marathonrt","provider":"DMark","version":"1.0","type":"link"}