Seraseq ctDNA Mutation Mix v2

SeraCareSKU: SER-0710-0144

Price:
$1,760

Description

To overcome the lack of patient-like reference materials for liquid biopsy, including drawbacks of existing methodologies such as sonication, SeraCare has developed a breakthrough technology that produces the most patient-like materials compared to native ctDNA. The Seraseq ctDNA Mutation Mix v2 is a highly multiplexed product for NGS-based ctDNA assays targeting cancer-relevant somatic mutations.

This specific ctDNA Mutation Mix v2 product it the wild-type with an allele frequency of 0%.

  • Size distribution, library yield and complexity consistent with native ctDNA
  • Single sample with 40 clinically-relevant mutations across 28 genes, all at the same specified allele frequency
  • Offered as a purified DNA mixture for ease of use during assay development
  • Mutation targets precisely quantitated with digital PCR
  • Single well-characterized GM24385 human genomic DNA as background wild-type material
  • Manufactured in GMP-compliant and ISO 13485-certified facilities

 

Specifications
# of Variants 40
Allele Frequency WT (0%)
Fragment Size ~170bp
Concentration 10 ng/µL
Fill Size 25 µL
Total DNA 250 ng
Buffer Tris/EDTA (TE)

 

NGS-Based Assay Compatibility Chart
Archer® Reveal ctDNA™ 28 Kit Oncomine® Pan-
Cancer Cell-Free Assay
Oncomine Lung
cfDNA Assay
Oncomine
Colon cfDNA
UltraSEEK™
Colon Panel
UltraSEEK
Lung Panel 
AKT1 AKT1 ALK AKT1 BRAF BRAF 
ALK ALK BRAF BRAF EGFR EGFR 
BRAF APC EGFR EGFR KRAS ERBB2 
CTNNB1 BRAF ERBB2 ERBB2 NRAS KRAS
EGFR CTNNB1 KRAS KRAS PIK3CA PIK3CA 
ERBB2 EGFR NRAS NRAS
IDH1 ERBB2 PIK3CA PIK3CA
KIT FGFR3 ROS1 SMAD4 
KRAS FLT3 TP53 TP53 
NRAS GNA11
PDGFRA GNAQ
PIK3CA GNAS
RET IDH1
ROS1 KIT
SMAD4 KRAS
TP53 NRAS
PDGFRA
PIK3CA
PTEN
TP53
ROS1
RET
Archer® is a registered trademark, and Reveal ctDNA™ is a trademark of ArcherDx, Inc.
Oncomine® is a registered trademark of Thermo Fisher Scientific.
UltraSEEK™ is a trademark of Agena Bioscience, Inc. 

 

Product Report

Package Insert

Product Sheet

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